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Resveratrol FAQ: Sirtuins, Life Extension, & Diet Information
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Resveratrol FAQ

Resveratrol FAQ

What is Resveratrol?

Resveratrol is a naturally-occurring compound known as a phytoalexin. It is produced by plants in response to attacks by pathogenic microorganisms or other harmful substances.

Where is Resveratrol found?

Resveratrol was first isolated from white hellebore and Japanese Knotweed in the1960s. However, Resveratrol was discovered in wine in 1992 attracting widespread attention since it was suggested that it contributed to the cardio-protective properties of wine.

Is Resveratrol available as a supplement?

Yes. Resveratrol supplements are available and the sales are continually increasing.

How does Resveratrol extend lifespan and delay aging?

Trans-Resveratrol, the active form of resveratrol polyphenols, was shown to activate what is so called the Sirtuin 1 (SIRT1) gene resulting in increased cell longevity and enhanced cellular productivity. SIRT1 is an enzyme that plays a major role in cellular regulation and longevity. Many studies concluded that trans-Resveratrol increased the lifespan of yeast and many animals. It is thought that the mechanism was through SIRT1 activation. Trans-Resveratrol was also shown to increase the number of cellular mitochondria thereby enhancing metabolism and increasing total produced energy. Those effects also contribute to the rejuvenating and anti-aging properties of Resveratrol.

What are the potential health benefits of Resveratrol?

It is thought that Resveratrol possesses an array of cardio-protective effects. This is due to the regulation of cholesterol levels and inhibition of multiple mechanisms involved in atherosclerosis.

It has been also shown that Resveratrol may have anti-diabetic properties by controlling glucose homeostasis and lipid metabolism.

Resveratrol was also shown to possess some antioxidant potential. Oxidants are harmful substances produced in the body and play a major role in cell death, aging and even cancer. Some studies even demonstrated anti-aging and anti-cancer properties of Resveratrol although those were done on plants and animals.

Are the health benefits of Resveratrol scientifically proven?

Any newly discovered drug or medication goes through many stages of trials and research before it can be tested on human beings in clinical trials. At this stage, all of those health benefits of Resveratrol have been demonstrated in animal studies which means that they will be tested soon on human beings. The numerous health benefits of Resveratrol made it a hot topic for medical research and we hope that studies and research will maximize those health benefits of Resveratrol.

Does Resveratrol have any side effects?

Since clinical trials on Resveratrol are lacking, reports on side effects of Resveratrol are lacking but it seems that it is generally safe. Some studies suggest that it may interfere with oral contraceptives. Also since its effects on growth are unknown, it is recommended that pregnant women and growing individuals should not consume Resveratrol at least until its safety in those cases is verified.



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